In biology, reprogramming refers to erasure and remodeling of epigenetic marks, such as DNA methylation, during mammalian development or in cell culture. [1] Such control is also often …

5 天之前 · Reprogramming antigen-specific T cells into pluripotent stem cells with unlimited self-renewal capacity represents an innovative and powerful strategy to overcome these …

2025年4月9日 · This review summarizes the recent advances in cell reprogramming mediated by transcription factors or chemical molecules, followed by elaborating on the important roles of …

2025年12月2日 · Cell reprogramming is the act of reverting mature, specialised cells into induced pluripotent stem cells, also known as iPS cells. This process requires a stem or progenitor cell …

To return an adult cell to a stem cell state, scientists package a stretch of DNA (called a plasmid) that carries the reprogramming instructions with a solution of lipids that help it melt through the …

2025年9月5日 · The human gut microbiome is a metabolically active and ecologically dynamic consortium that profoundly influences host physiology, in part by modulating epigenetic …

In addition to problems of safety, reprogramming thus far been a very inefficient process – only about one in every 1,000 mature cells is successfully reprogrammed.

Biol. Reprod. 69 (3): 902–14. doi: 10.1095/biolreprod.103.017293. PMID 12748125. ^ Wrenzycki C, Niemann H (2003). “Epigenetic reprogramming in early embryonic development: effects of …

Reprogramming refers to a reversible shift in the gene expression of cells, leading to abnormal molecular and anatomical states. This process has been observed in retinal stress, particularly …

2026年1月12日 · Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, which are infection and tumor-fighting white …