Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Researchers used spatial transcriptomics to map gene expression in developing wheat spikes at single-cell resolution.

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Researchers at the John Innes Center and the Earlham Institute are pioneering powerful single-cell visualization techniques ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

The partners are launching ImmuneScape, a multiomics program using spatial and single-cell sequencing to study immune drivers ...