One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

In diagrams and illustrations of cells, DNA is sometimes shown as a mass in the cell's nucleus, like a bowl of ramen noodles. For many years, it's been standard practice to take images of cells that ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

Researchers have identified how the architecture of the cell nucleus can change gene activity in plants. This discovery reveals fundamental knowledge about genome regulation and points towards future ...

The artificial cell nucleus (right) constructed using the purified DNA was morphologically very similar to the natural cell nucleus derived from an egg (left). A team led by Professor Kazuo Yamagata ...

Left: staining for H3K27me3, which marks inactive DNA, on a nucleus of a wildtype embryo consisting of two cells Right: staining for H3K27me3, which marks inactive DNA, on a nucleus of an embryo ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

In an era where the U.S. healthcare system spends $4.5T annually yet faces systemic failures, with life expectancy plummeting to a three-decade low and chronic disease rates at an all-time high, the ...