Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 32 (August 9, 2016), pp. 9057-9062 (6 pages) UV-induced DNA lesions are important contributors to ...

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...

Tumor-Infiltrating Lymphocyte Function Predicts Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Oxaliplatin forms part of routine treatment of advanced colorectal cancer; ...

This is a preview. Log in through your library . Abstract We have adapted the eXcision Repair-sequencing (XR-seq) method to generate single-nucleotide resolution dynamic repair maps of UV-induced ...

Activity of antibody-drug conjugates (ADCs) with radiation in preclinical bladder cancer models. This is an ASCO Meeting Abstract from the 2024 ASCO Genitourinary Cancers Symposium. This abstract does ...