Twenty-week-old male SHR and WKY rats were used in this study. All protocols were approved by the Institutional Animal Care and Use Committee (IACUC) at the Medical College of Shihezi University and ...

Signaling through gap junctions (electrical synapses) is important in the development of the mammalian central nervous system. Abundant between neurons during postnatal development, gap junction ...

Ischemia reperfusion injury (IRI) is one of the main cause of organ dysfunction after heart attack and solid organ transplantation, and occurs frequently when the new organ comes from a deceased ...

Researchers at the University of California, San Francisco (UCSF) have found that cells from triple-negative breast cancer (TNBC) form direct connections with nearby fat cells to access energy needed ...

Neighboring cells exchange molecular information via channels that directly connect them. Disruption of this signaling system can lead to disorders ranging from hearing loss to heart disease Like ...

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Adeno-associated virus vector containing an adenine base editor provides an effective strategy to treat hereditary hearing loss caused by the R75W mutation. Moreover, this gene editing technology can ...

A new study in mice has identified a cellular communication system in the brain’s blood vessels that helps direct blood flow to regions that are active and in need of oxygen and nutrients. The ...