Dihydropteroate synthase (DHPS) is a crucial enzyme in the folate biosynthetic pathway, catalysing the formation of essential folate cofactors that underpin DNA synthesis and cellular functioning.

Knee cartilage usually wears down quietly. Over time, that loss can turn walking stairs into a daily calculation.

Every year, millions of infants and children undergo surgery under general anesthesia in the world. Sevoflurane is a commonly ...

Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate ...

A new study has created a highly selective inhibitor for Matrix Metallopeptidase 7 (MMP7), an enzyme important for cancer spread and progression. Using advanced peptide discovery technology, ...

Researchers at Queen Mary University of London’s School of Biological and Behavioural Sciences, using the simple fission yeast as a model, have shown that a new target of rapamycin (TOR) inhibitor, ...

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of ...

Scientists have long assumed that once the smooth cartilage in a damaged knee wears away, the body has little chance of restoring it. A new line of research is challenging that assumption by showing ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...