The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP ...

Repetitive DNA and the D1 protein help matching fruit fly chromosomes recognize one another before eggs form.

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...

For decades, plant biotechnologists have relied on a soil bacterium with an extraordinary talent: the ability to smuggle ...

Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter have discovered a new property of the molecular motors that shape our chromosomes. While six years ...

Noah A. Dusseau is in the Department of Physiology, College of Natural Science, Michigan State University, East Lansing, Michigan 48824, USA. Read the paper: Genetic elements promote retention of ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

A new study conducted on roundworms finds that a common plastic ingredient causes breaks in DNA strands, resulting in egg cells with the wrong number of chromosomes. Monica Colaiácovo of Harvard ...

Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...

I completed a master's degree in a science graduate program and work as a researcher at a manufacturing company. At "Kenro," ...

Japanese researchers used CRISPR-Cas9 to remove the extra chromosome 21 from cells in a lab. It’s a real breakthrough — but ...