疱疹病毒是一种广泛存在的双链DNA病毒，具有终生潜伏期，可引起多种疾病。尽管靶向DNA聚合酶的抗病毒药物是有效的，但不断增加的耐药性强调了寻找替代药物的必要性。解旋酶-引物酶抑制剂（HPIs）是一种很有前途的抗病毒药物，但其作用机制尚不明确。此外，解 ...

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications. Now, a new ...

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...

Artios Pharma Limited (“Artios”), a biopharmaceutical company committed to realizing the therapeutic power of targeting the DNA damage response (“DDR”) in cancer, today announced that it will present ...

Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA and RNA. PCR involves the enzymatic amplification of ...