Precision gene editing can be achieved by base editing, nucleotide editing, or editing of small or large gene fragments. The specific mechanisms include various DNA repair pathways. Many precision ...

Manipulating “thresholds” with mitochondrial gene editing tools. By focusing on the genetic roots of neurodegenerative diseases, mitochondrial DNA editing represents a shift in therapeutic strategies.

New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime ...

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known 'gene scissor' but is much smaller and thus easier to ...

Genome editing is a powerful biotechnology tool that allows scientists to make precise changes to an organism's DNA. It involves the use of specialized enzymes, known as engineered nucleases or ...

Gene editing is a group of technologies that enable scientists to precisely alter an organism's DNA. These technologies allow for the addition, removal, or alteration of genetic material at specific ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

A groundbreaking gene-editing method from UT Austin is changing the game for treating complex genetic diseases like cystic fibrosis, hemophilia, and Tay Sachs. Using retrons—DNA tools borrowed from ...

The energy factories in our cells contain their own genes, and genetic mutations in them can cause deadly inherited diseases. These oblong-shaped organelles, or mitochondria, translate genes into ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...