Researchers from the Wellcome Sanger Institute and collaborators used human stem cells and neurons to investigate what features influence how well CRISPR activation works for different sets of genes.

Since the discovery of CRISPR/Cas9 a decade ago, scientists have been able to change the genetic code of living organisms; however, this first generation of technology could only remove or replace ...

Identifying a few key genes within the vastness of the human genome was once akin to finding the proverbial needle in a haystack. But with the introduction of functional genomic screening, scientists ...